Oestra® is available in two formulations—Oestra® Menopause and Oestra® Start - both designed to provide full-body hormone support using bioidentical hormones.
While they share the same delivery method, they differ in strength, intensity, and how your body responds to them.
The Core Difference
The key difference is the level of hormone support:
Oestra® Menopause → Lower-dose, gentler support
Oestra® Start → Higher-dose, more intensive support
Both are effective—they’re simply designed for different needs and experiences.
Oestra® Menopause: Gentle, Steady Support
What it contains:
Estradiol: 0.5 mg
Progesterone: 50 mg
This formulation is designed to:
Provide foundational hormone support
Support a gradual, comfortable adjustment
Minimize the likelihood of spotting, cramping, or side effects
What it supports
Even at a lower dose, it can help with:
Sleep
Mood stability
Brain fog
Vaginal dryness
Skin and hair
Energy and joint comfort
What it may feel like
Smoother, more gradual changes
Fewer noticeable side effects early on
A steady build in symptom relief over time
Oestra® Start: Stronger, Deeper Support
What it contains:
Estradiol: ~2 mg
Progesterone: ~80 mg
This higher-dose formulation is designed to:
Deliver more robust hormone support
Address more persistent or intense symptoms
Create stronger systemic effects
What it may feel like
Because it’s more potent, some women may notice:
Faster or more noticeable symptom changes
Temporary spotting, cramping, or breast tenderness
Short-term bloating or adjustment symptoms
These effects are typically part of the initial adjustment phase and tend to resolve.
Side-by-Side Comparison
Feature | Oestra® Menopause | Oestra® Start |
Hormone Strength | Lower dose | Higher dose |
Estradiol | 0.5 mg | ~2 mg |
Progesterone | 50 mg | ~80 mg |
Adjustment Experience | Smoother, gentler | More noticeable initially |
Likelihood of Spotting | Lower | Higher (early phase) |
Symptom Support | Foundational | More intensive |
Can You Switch Between Formulas?
Your treatment can absolutely evolve over time—but any changes to your formula or dose must be guided by a licensed provider.
If you are:
Thinking about switching formulas
Wanting a higher or lower dose
Experiencing symptoms you’d like to improve
Feeling unsure about your current plan
👉 The next step is to book a consult with one of our providers.
They will:
Review your symptoms and history
Assess how your body is responding
Recommend the safest and most effective option for you
Why a Provider Consult Is Important
Oestra® is a medical therapy, and even small adjustments can meaningfully change how your body responds.
A provider ensures:
Your hormones stay balanced and safe
Your dose is appropriate for your needs
Any symptoms are addressed thoughtfully
Self-adjusting or switching without guidance can lead to:
Unnecessary side effects
Hormone imbalance
Less optimal results
What to Expect During Any Transition
If your provider recommends a change, you may notice:
Temporary adjustment symptoms (spotting, cramping, breast tenderness)
A short period of recalibration as your body adapts
These changes are typically temporary and manageable with support.
The Bottom Line
Both Oestra® Menopause and Oestra® Start:
Use bioidentical hormones
Provide systemic, full-body support
Are designed to support you at different levels
The difference is simply how much support your body needs—and when.
We’re Here to Support You
If you’re considering a change or have questions about your current formula, the best next step is to schedule a provider consult so we can guide you safely and effectively.
You’re not expected to figure this out on your own—we’re here every step of the way.