FAQs: Oestra®

Oestra™ is designed to prevent the dominance of testosterone or estradiol, a common issue when hormones are given one at a time.
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Oestra® supports hormonal balance by restoring estrogen and progesterone, which helps the body naturally rebalance other hormones - including testosterone.

While Oestra® does not contain testosterone, our bodies are highly intelligent and naturally convert some progesterone into testosterone as part of normal hormone physiology. Thanks to Oestra’s high bioavailability (approximately 70%), there is enough progesterone in each dose to support both progesterone needs and the body’s natural testosterone production.

In this way, Oestra® helps create a hormonal environment that supports balance across estrogen, progesterone, and testosterone - without adding testosterone directly.

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For most clients, we recommend a 2-week overlap period when starting Oestra®.

This means:

This gradual transition helps support more stable hormone levels and may reduce the likelihood of experiencing symptoms related to sudden hormonal changes.

Important Exceptions

Do not begin Oestra® immediately after receiving a new pellet insertion.
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Ideally, you should be approaching the end of your pellet cycle (typically around 3 months after insertion) before beginning Oestra®. This allows most of the previously implanted hormones to naturally decline.
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Starting too soon may result in excessive hormone overlap and unwanted side effects.

If you are currently using hormone injections please reach out to our Clinical Team before beginning your transition.
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Injection schedules and hormone levels can vary significantly from person to person, and our clinicians can help determine the safest timing for your switch.
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For more detailed information, go here: Oestra® and HRT

Yes. Oestra™ is not a form of birth control and it’s possible to get pregnant while on it. We recommend non-oral forms of birth control (such as an IUD) if you are using it alongside Oestra™ .

Yes, absolutely. Progesterone is critical for balancing estradiol throughout the entire body, not just the uterus. It supports the health of your skin, hair, heart, bones, brain, and mood .

Labs are often unreliable due to the constantly fluctuating nature of hormones, and there is no way to predict your optimal dose from a lab test alone. Instead, we start you on a carefully selected dose and adjust based on your real-life symptoms and progress .
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Yes, this is very common and often a sign of iodine deficiency, which causes fibrocystic breast disease. Starting a daily iodine supplement usually helps alleviate the tenderness within a few weeks.
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Yes—technically, you are still considered to be in menopause if your body is no longer producing its own hormones.

However, with Oestra®, your body is receiving the hormonal support it needs, so you may not feel or function like a typical menopausal woman.

By restoring estrogen and progesterone levels, Oestra® helps your body move out of a depleted hormonal state. This often leads to improvements in energy, mood, strength, recovery, and overall well-being.

So while your biological status remains menopause, your day-to-day experience can feel very different—more balanced, supported, and aligned with how your body is meant to function.